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Effect of stent oversizing on in-stent stenosis and lumen size in normal porcine veins.
- Source :
-
Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists [J Endovasc Ther] 2005 Aug; Vol. 12 (4), pp. 495-502. - Publication Year :
- 2005
-
Abstract
- Purpose: To present an in vivo evaluation of the effects of stent oversizing on in-stent stenosis and on actual lumen size in normal veins.<br />Methods: Twelve self-expanding stents were implanted in the common iliac veins of 6 minipigs, which were divided in 2 groups for follow-up at 1 and 3 months, respectively. Oversizing ranged from 119.5% to 216% of the original vessel diameter. Intravascular ultrasound (IVUS) was used to measure vessel areas at the stent edges and midpoint. In-stent stenosis and decrease in actual lumen size were evaluated with IVUS immediately after implantation and during follow-up.<br />Results: There was a very strong positive linear regression between stent oversizing and in-stent stenosis in the 1-month model (r=0.947, p=0.004), in the 3-month model (r=0.931, p=0.007), and in the sum of these 2 groups (r=0.83, p<0.001). Regarding the change in actual lumen size, we found a strong negative linear regression with stent oversizing in the 1-month (r=-0.754, p=0.083) and the 3-month (r=-0.562, p=0.246) groups, but these did not attain statistical significance. However, a strong correlation between stent oversizing and a decrease in lumen size in all samples proved to be statistically significant (r=0.619, p=0.032).<br />Conclusions: Stent oversizing was strongly correlated with increased in-stent stenosis and decreased actual lumen size at follow-up in normal non-stenotic porcine veins.
- Subjects :
- Analysis of Variance
Animals
Biopsy, Needle
Equipment Design
Equipment Failure
Equipment Safety
Iliac Vein pathology
Immunohistochemistry
Linear Models
Male
Models, Animal
Probability
Recurrence
Reference Values
Sensitivity and Specificity
Swine
Ultrasonography, Interventional
Angioplasty, Balloon instrumentation
Iliac Vein diagnostic imaging
Stents adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 1526-6028
- Volume :
- 12
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists
- Publication Type :
- Academic Journal
- Accession number :
- 16048382
- Full Text :
- https://doi.org/10.1583/05-1534.1