Back to Search Start Over

Plexiform fibrohistiocytic tumor: three unusual cases occurring in infancy.

Plexiform fibrohistiocytic tumor: three unusual cases occurring in infancy.

Authors :
Leclerc S
Hamel-Teillac D
Oger P
Brousse N
Fraitag S
Source :
Journal of cutaneous pathology [J Cutan Pathol] 2005 Sep; Vol. 32 (8), pp. 572-6.
Publication Year :
2005

Abstract

Background: Plexiform fibrohistiocytic tumor is a soft-tissue tumor of intermediate malignancy occurring in children and young adults but is only rarely found in infants. The tumor usually involves the upper limbs and is slow growing and painless. Recurrence rate is high. Lymph node and systemic metastases can occur, but have never been reported in infants. Clinical behavior in infancy is not known. Histologically, the tumor is characterized by nodules of histiocyte-like and multinucleated cells and fascicles of spindle cells arranged in a plexiform pattern. Mitosis, atypia, and nuclear pleomorphism are common but not pronounced.<br />Methods and Results: We report three cases in infants, one of which is congenital, having an unusual topography and a broad histological spectrum.<br />Conclusion: In infants, wide excision with large safety margins should be performed as the behaviour of this tumor remains uncertain. Leclerc S, Hamel-Teillac D, Oger P, Brousse N, Fraitag S. Plexiform fibrohistiocytic tumor: three unusual cases occurring in infancy.

Details

Language :
English
ISSN :
0303-6987
Volume :
32
Issue :
8
Database :
MEDLINE
Journal :
Journal of cutaneous pathology
Publication Type :
Academic Journal
Accession number :
16115057
Full Text :
https://doi.org/10.1111/j.0303-6987.2005.00334.x