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Aspirochlorine class compounds from Aspergillus flavus inhibit azole-resistant Candida albicans.
- Source :
-
Journal of natural products [J Nat Prod] 2005 Aug; Vol. 68 (8), pp. 1300-2. - Publication Year :
- 2005
-
Abstract
- Dereplication of the antifungal extracts of Aspergillus flavus indicated that the primary antifungal compound present was the known aspirochlorine (1). Preparative isolation work resulted in the identification of the new compounds tetrathioaspirochlorine (2) and cyclo(D-N-methyl-Leu-L-Trp) (3).
- Subjects :
- Antifungal Agents chemistry
Antifungal Agents pharmacology
Microbial Sensitivity Tests
Molecular Structure
Mycotoxins chemistry
Mycotoxins classification
Mycotoxins pharmacology
Spiro Compounds chemistry
Spiro Compounds classification
Spiro Compounds pharmacology
Antifungal Agents isolation & purification
Aspergillus flavus chemistry
Azoles pharmacology
Candida albicans drug effects
Drug Resistance, Fungal
Mycotoxins isolation & purification
Spiro Compounds isolation & purification
Subjects
Details
- Language :
- English
- ISSN :
- 0163-3864
- Volume :
- 68
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Journal of natural products
- Publication Type :
- Academic Journal
- Accession number :
- 16124785
- Full Text :
- https://doi.org/10.1021/np050141k