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Rational control of enantioselectivity of lipase by site-directed mutagenesis based on the mechanism.
- Source :
-
Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2005 Oct 07 (37), pp. 4650-1. Date of Electronic Publication: 2005 Aug 12. - Publication Year :
- 2005
-
Abstract
- The enantioselectivity of a Burkholderia cepacia lipase toward secondary alcohols could be both increased and decreased rationally by introducing only a single mutation on the basis of the mechanism proposed previously.
Details
- Language :
- English
- ISSN :
- 1359-7345
- Issue :
- 37
- Database :
- MEDLINE
- Journal :
- Chemical communications (Cambridge, England)
- Publication Type :
- Academic Journal
- Accession number :
- 16175280
- Full Text :
- https://doi.org/10.1039/b508244g