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The Arabidopsis leaf as a model system for investigating the role of cell cycle regulation in organ growth.
- Source :
-
Journal of plant research [J Plant Res] 2006 Jan; Vol. 119 (1), pp. 43-50. Date of Electronic Publication: 2005 Nov 15. - Publication Year :
- 2006
-
Abstract
- The role of cell cycle regulation and cell division in plant growth and organ development is controversial. Some experimental data are most easily interpreted from the 'cellular perspective' that cell division drives growth, whereas other observations are more consistent with the 'organismal perspective' that cell division is merely a consequence of growth, and to a large extent facultative. Here we develop a model of cell cycle regulation in the context of leaf development based on literature, published kinematic analysis, flow-cytometric and transcriptomic data obtained from growing Arabidopsis leaves. We tested this model by comparing the in silico inhibition of the cell cycle progression with the experimental observations of transgenic plants overexpressing the cell cycle inhibitor Arath;KRP2. The model simulates the behaviour of proliferating cells quite well, but is inadequate in describing the effects on expanding cells. This may point to a difference in the nature of the expansion process during the proliferating and non-dividing phase of leaf development.
- Subjects :
- Biomechanical Phenomena
Cell Cycle genetics
Cyclin-Dependent Kinases genetics
Cyclin-Dependent Kinases physiology
Flow Cytometry
Gene Expression Regulation, Developmental
Gene Expression Regulation, Plant
Morphogenesis genetics
Oligonucleotide Array Sequence Analysis
Arabidopsis growth & development
Cell Cycle physiology
Models, Biological
Morphogenesis physiology
Plant Leaves growth & development
Subjects
Details
- Language :
- English
- ISSN :
- 0918-9440
- Volume :
- 119
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Journal of plant research
- Publication Type :
- Academic Journal
- Accession number :
- 16292465
- Full Text :
- https://doi.org/10.1007/s10265-005-0234-2