A new antibacterial clerodane diterpenoid from the resinous exudate of Haplopappus uncinatus.

Authors :: Urzúa A
Jara F
Tojo E
Wilkens M
Mendoza L
Rezende MC
Source :: Journal of ethnopharmacology [J Ethnopharmacol] 2006 Jan 16; Vol. 103 (2), pp. 297-301. Date of Electronic Publication: 2005 Nov 28.
Publication Year :: 2006
Abstract: The antibacterial activity of Haplopappus uncinatus is attributed to a new clerodane diterpenoid, 18-acetoxy-cis-cleroda-3-en-15-oic acid (10 betaH, 16 xi 19 beta, 17beta, 20 alpha form) (1), isolated as a major component from the resinous exudates of its twigs and leaves, together with the inactive 3,5-dihydroxy-6,7,3',4'-tetramethoxyflavone, n-alkanes and a few sesquiterpenoids.

Subjects :: Anti-Infective Agents isolation & purification
Diterpenes isolation & purification
Microbial Sensitivity Tests
Plant Extracts isolation & purification
Structure-Activity Relationship
Anti-Infective Agents chemistry
Diterpenes chemistry
Haplopappus
Plant Extracts chemistry

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