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Immune reconstitution inflammatory syndrome in HIV-infected patients with disseminated histoplasmosis.
- Source :
-
AIDS (London, England) [AIDS] 2006 Jan 02; Vol. 20 (1), pp. 119-21. - Publication Year :
- 2006
-
Abstract
- Four HIV-1-infected patients presented with unusual clinical manifestations in the course of disseminated histoplasmosis, including liver abscesses, compressive lymphadenitis, intestinal obstruction, uveitis and arthritis within a median of 45 days after initiation of highly active antiretroviral therapy (HAART). They had a median increase of 106 CD4 cells/mul and granulomas with caseation in three. Partial immune reconstitution induced by HAART during disseminated histoplasmosis either related to the variety capsulatum or duboisii may be associated with immune reconstitution inflammatory syndrome.
- Subjects :
- AIDS-Related Opportunistic Infections immunology
Adult
Antifungal Agents therapeutic use
Antiretroviral Therapy, Highly Active adverse effects
Female
HIV Infections drug therapy
Humans
Immunity, Cellular
Itraconazole therapeutic use
Male
Middle Aged
Syndrome
Treatment Outcome
HIV Infections immunology
Histoplasmosis immunology
Subjects
Details
- Language :
- English
- ISSN :
- 0269-9370
- Volume :
- 20
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- AIDS (London, England)
- Publication Type :
- Academic Journal
- Accession number :
- 16327328
- Full Text :
- https://doi.org/10.1097/01.aids.0000199014.66139.39