Hypoxia-simulating agents selectively stimulate arsenic trioxide-induced growth arrest and cell differentiation in acute promyelocytic leukemic cells.

Subjects

Subjects :

Arsenic Trioxide
Cell Differentiation drug effects
Cell Division drug effects
Humans
Hypoxia-Inducible Factor 1, alpha Subunit metabolism
Leukemia, Promyelocytic, Acute drug therapy
Leukemia, Promyelocytic, Acute genetics
Neoplasm Proteins metabolism
Oncogene Proteins, Fusion metabolism
Tretinoin pharmacology
Tretinoin therapeutic use
U937 Cells drug effects
Antineoplastic Agents pharmacology
Arsenicals pharmacology
Cell Hypoxia drug effects
Cobalt pharmacology
Deferoxamine pharmacology
Leukemia, Promyelocytic, Acute pathology
Oxides pharmacology

Details

Language :

English

ISSN :

1592-8721

Volume :

90

Issue :

12

Database :

MEDLINE

Journal :

Haematologica

Publication Type :

Academic Journal

Accession number :

16330421