Hypoxia down-regulates cyclic guanidine monophosphate-dependent protein kinase in fetal pulmonary vascular smooth muscle cell through generation of reactive oxygen species and promotes development of pulmonary hypertension.

Subjects

Subjects :

Animals
Down-Regulation
Myoblasts physiology
Sheep
Cyclic GMP-Dependent Protein Kinases metabolism
Fetal Hypoxia physiopathology
Hypertension, Pulmonary etiology
Pulmonary Artery physiopathology
Reactive Oxygen Species metabolism

Details

Language :

English

ISSN :

0012-3692

Volume :

128

Issue :

6 Suppl

Database :

MEDLINE

Journal :

Chest

Publication Type :

Academic Journal

Accession number :

16373839

Full Text :

https://doi.org/10.1378/chest.128.6_suppl.577S-a