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Childhood acute lymphoblastic leukaemia in relation to population mixing around the time of birth in South Hungary.
- Source :
-
Pediatric blood & cancer [Pediatr Blood Cancer] 2006 Dec; Vol. 47 (7), pp. 944-8. - Publication Year :
- 2006
-
Abstract
- In a retrospective epidemiological study of 481,984 live births in South Hungary, we investigated whether higher levels of population mixing around the time of birth is a risk factor for acute lymphoblastic leukemia (ALL) under age 5 years. Poisson regression was used to investigate the relationship between risk of ALL and the population-mixing index based on the number of incomers in each county district for each year, standardized to have a range of 0-1. Among all children, the risk of ALL increased significantly with increasing population mixing around the time of birth (trend across the range of 0-1 RR = 2.1 95% CI: 1.02-4.44). This effect was more marked for boys (RR = 3.1 95% CI: 1.13-8.51), which supports a sex-specific effect of exposures on risk of ALL.
Details
- Language :
- English
- ISSN :
- 1545-5009
- Volume :
- 47
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- Pediatric blood & cancer
- Publication Type :
- Academic Journal
- Accession number :
- 16421899
- Full Text :
- https://doi.org/10.1002/pbc.20737