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Postrenal transplant non-EBV multiple myeloma of donor origin.
- Source :
-
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2006 Feb; Vol. 6 (2), pp. 419-22. - Publication Year :
- 2006
-
Abstract
- Multiple myeloma occurring after solid organ transplantation is a rare condition, with only a few case reports found in the literature. We report a case of Epstein-Barr virus-negative, posttransplant multiple myeloma in a 67-year-old female, presenting 18 months after renal transplantation. Interestingly, fluorescence in situ hybridization analysis of the tumor revealed a Y chromosome in the majority of the cells, indicating that the neoplasm was derived from the donor kidney. To our knowledge, this represents the first reported case with these features.
- Subjects :
- Aged
Bone Marrow pathology
Chromosomes, Human, Y
Female
Herpesvirus 4, Human isolation & purification
Humans
In Situ Hybridization, Fluorescence
Kidney Transplantation pathology
Multiple Myeloma genetics
Multiple Myeloma pathology
Postoperative Complications pathology
Tissue Donors
Kidney Failure, Chronic surgery
Kidney Transplantation adverse effects
Multiple Myeloma etiology
Postoperative Complications diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1600-6135
- Volume :
- 6
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
- Publication Type :
- Academic Journal
- Accession number :
- 16426330
- Full Text :
- https://doi.org/10.1111/j.1600-6143.2005.01170.x