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Insulin resistance, obesity, and metabolic syndrome among non-diabetic pre- and post-menopausal women in North Taiwan.
- Source :
-
International journal of obesity (2005) [Int J Obes (Lond)] 2006 Jun; Vol. 30 (6), pp. 912-7. - Publication Year :
- 2006
-
Abstract
- Objective: To investigate the relationship between the metabolic syndrome and its related factors among non-diabetic pre- and post-menopausal women in North Taiwan.<br />Design: A cross-sectional study in a medical center in North Taiwan.<br />Subjects: Five hundred and ninety-four, non-diabetic middle-aged women (age range=40-64 years, mean=48.9+/-5.4 years) were recruited.<br />Measurements: The fasting plasma glucose, insulin, lipids levels and anthropometric indices were measured. The homeostasis model assessment was applied to estimate the degree of insulin resistance (HOMA-IR). Metabolic syndrome was defined by using the National Cholesterol Education Panel (NCEP) criteria and modified NCEP criteria (waist circumference >80 cm).<br />Results: The prevalence of metabolic syndrome was 6.2% using NCEP criteria, and 8.9% using modified NCEP criteria. Post-menopausal women had a higher prevalence of metabolic syndrome and its individual components compared to pre-menopausal women except hyperglycemia and low HDL-C. In multiple logistic regression analysis with adjustment for age and menopausal status, both BMI and HOMA-IR were independently associated with the metabolic syndrome.<br />Conclusion: The prevalence of metabolic syndrome was higher in post-menopausal than pre-menopausal women. Both obesity and insulin resistance may play an important role in the development of metabolic syndrome among the middle-aged women in North Taiwan.
- Subjects :
- Adult
Anthropometry
Asian People
Blood Glucose metabolism
Blood Pressure
Body Mass Index
Cross-Sectional Studies
Diabetes Complications
Female
Humans
Insulin blood
Lipids blood
Metabolic Syndrome blood
Metabolic Syndrome ethnology
Middle Aged
Obesity blood
Obesity ethnology
Postmenopause blood
Premenopause blood
Prevalence
Taiwan epidemiology
Insulin Resistance
Metabolic Syndrome etiology
Obesity complications
Subjects
Details
- Language :
- English
- ISSN :
- 0307-0565
- Volume :
- 30
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- International journal of obesity (2005)
- Publication Type :
- Academic Journal
- Accession number :
- 16432538
- Full Text :
- https://doi.org/10.1038/sj.ijo.0803240