Back to Search
Start Over
Factor VIIa inhibitors: improved pharmacokinetic parameters.
- Source :
-
Bioorganic & medicinal chemistry letters [Bioorg Med Chem Lett] 2006 Apr 15; Vol. 16 (8), pp. 2243-6. Date of Electronic Publication: 2006 Feb 07. - Publication Year :
- 2006
-
Abstract
- Efforts to improve the potency and pharmacokinetic properties of small molecule factor VIIa inhibitors are described. Small structural modifications to existing leads allow the modulation of half-life and clearance, potentially making these compounds suitable candidates for drug development.
Details
- Language :
- English
- ISSN :
- 0960-894X
- Volume :
- 16
- Issue :
- 8
- Database :
- MEDLINE
- Journal :
- Bioorganic & medicinal chemistry letters
- Publication Type :
- Academic Journal
- Accession number :
- 16455251
- Full Text :
- https://doi.org/10.1016/j.bmcl.2006.01.037