Smooth muscle research: from Edith Bülbring onwards.

The properties of smooth muscle are currently being studied extensively. Indeed, the small size of myocytes and the huge range of behaviours they exhibit make them an attractive focus for current research. However, this was not always the case. These properties initially made smooth muscles more difficult to study than the larger specialized striated muscles that were the focus of attention of leading researchers. In the UK, research into the physiology of smooth muscles began in the Pharmacology Department at Oxford, led by Edith Bülbring; her early results attracted much attention and resulted in the formation of an active international smooth muscle research group. Although several areas of current interest in the field of smooth muscle were not tackled by the Oxford group, progression of much of the field has clear links to Bülbring and her group.