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[Analysis of the possible involvement of the glutamate transporter gene EAAT2 and the glutamate receptor genes GRIA1 and GRIA2 in pathogenesis of motor neuron disease in the Russian population].

Authors :
Zherebtsova AL
Shadrina MI
Semenova EV
Levitskiĭ GN
Alekhin AV
Slominskiĭ PA
Skvortsova VI
Limborskaia SA
Source :
Genetika [Genetika] 2006 Jan; Vol. 42 (1), pp. 104-9.
Publication Year :
2006

Abstract

Polymorphisms of the genes of the glutamatergic system EAAT2, GRIA1, and GRIA2 have been analyzed in patients with sporadic motor neuron disease (MND) from Russia. The disease is not associated with polymorphic alleles of the genes studied, which indicates that EAAT2, GRIA1, and GRIA2 play an insignificant role in the pathogenesis of sporadic MND.

Details

Language :
Russian
ISSN :
0016-6758
Volume :
42
Issue :
1
Database :
MEDLINE
Journal :
Genetika
Publication Type :
Academic Journal
Accession number :
16523673