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[Phototype, vitamin D status and bone mineral density among women at risk of osteoporosis].

Authors :
Guinot C
Ezzedine K
Mauger E
Ambroisine L
Latreille J
Bertrais S
Preziosi P
Galan P
Chapuy MC
Arnaud S
Meunier PJ
Tschachler E
Hercberg S
Malvy D
Source :
La Revue de medecine interne [Rev Med Interne] 2006 May; Vol. 27 (5), pp. 369-74. Date of Electronic Publication: 2006 Mar 03.
Publication Year :
2006

Abstract

Purpose: The aim of this study was to test the influence of phototype and vitamin D status feature on the bone mineral density (BMD) of the femoral neck in a group of middle-aged women considered at risk of osteoporosis (low levels of vitamin D [25(OH)D3<78 nmol/L] and hyperparathyroidism [parathormone level>36 pg/mL]).<br />Methods: This two-step study was conducted on 122 French women enrolled in the SUVIMAX (supplémentation en vitamines et minéraux antioxydants: antioxidant vitamin and mineral supplementation) cohort. The impact of various variables on BMD, including age, body mass index (BMI), vitamin D status, alcohol intake, sun exposure intensity and phototype was investigated using regression models.<br />Results: No statistical link was found between BMD and the variables documenting vitamin D status and parathormone levels, nor phototype. Nevertheless, fair phototypes tended to be associated with lower BMD values. However, BMD decreased with age and increased with BMI and physical activity level.<br />Conclusions: Whatever their phototype, adult women concerned about precarious vitamin D status should undergo a vitamin D supplementation in combination with an adequate calcium intake all year long and a proper sun protection. Moreover, a physical activity maintenance should provide an additional benefit for prevention of osteoporosis.

Details

Language :
French
ISSN :
0248-8663
Volume :
27
Issue :
5
Database :
MEDLINE
Journal :
La Revue de medecine interne
Publication Type :
Academic Journal
Accession number :
16563573
Full Text :
https://doi.org/10.1016/j.revmed.2006.01.020