Disseminated vitiligo associated with AIDS.

We report a case of vitiligo arising one year after human immunodeficiency virus (HIV) seropositivity but before clinical onset of acquired immunodeficiency syndrome (AIDS). To our knowledge, this specific time sequence has not been described. Generalization of such lesions began during a period of medical noncompliance, increasing viral load, rising CD8+ count, and markedly decreased CD4+ count. These findings suggest new mechanisms of autoimmune and infectious pathogenesis.