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ESCRT complexes assembled and GLUEd.
- Source :
-
Structure (London, England : 1993) [Structure] 2006 Apr; Vol. 14 (4), pp. 631-2. - Publication Year :
- 2006
-
Abstract
- The ESCRT-I, -II, and -III complexes act sequentially to sort monoubiquitinated transmembrane proteins into multivesicular bodies for targeted degradation in the lysosome. Two papers published in a recent issue of Cell provide insights into the structural organization and functional interactions of the ESCRT-I complex and ESCRT-II GLUE domain.
- Subjects :
- Animals
Cell Membrane metabolism
Endosomes chemistry
Lysosomes metabolism
Models, Biological
Models, Genetic
Models, Molecular
Molecular Conformation
Phosphatidylinositol Phosphates chemistry
Protein Binding
Protein Conformation
Protein Structure, Tertiary
Protein Transport
Ubiquitin chemistry
Endosomes metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 0969-2126
- Volume :
- 14
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Structure (London, England : 1993)
- Publication Type :
- Periodical
- Accession number :
- 16615903
- Full Text :
- https://doi.org/10.1016/j.str.2006.03.005