Magnesium supplementation as an adjuvant to synthetic calcium channel antagonists in the treatment of hypertension.

Authors :: Touyz RM
Source :: Medical hypotheses [Med Hypotheses] 1991 Oct; Vol. 36 (2), pp. 140-1.
Publication Year :: 1991
Abstract: Magnesium (Mg2+) has antagonistic properties to calcium (Ca2+) and has been termed the physiologic Ca2+ blocker. Synthetic Ca2+ channel blockers are extensively used as anti-hypertensive agents. It is hypothesised that when administered in combination synthetic Ca2+ channel blockers and Mg are synergistic in the treatment of hypertension.

Subjects :: Calcium Channels physiology
Drug Synergism
Drug Therapy, Combination
Humans
Hypertension physiopathology
Models, Biological
Muscle, Smooth, Vascular physiopathology
Calcium Channel Blockers therapeutic use
Hypertension drug therapy
Magnesium therapeutic use

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