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Liver retransplantation: report of 80 cases and review of literature.
- Source :
-
Hepatobiliary & pancreatic diseases international : HBPD INT [Hepatobiliary Pancreat Dis Int] 2006 May; Vol. 5 (2), pp. 180-4. - Publication Year :
- 2006
-
Abstract
- Background: Because the orthotopic liver transplantation (OLT) was performed widely in recent 5 years throughout China, the proportion of recipients whose graft function deteriorated to be retransplantation candidates increased gradually. This study was undertaken to analyze clinical experience of orthotopic liver retransplantation (re-OLT) at our center.<br />Methods: The medical records of 80 patients who had undergone liver retransplantation at our center from January 1999 to July 2005 were analyzed retrospectively, including indications and timing of retransplantation, surgical techniques, and the causes of death.<br />Results: The commonest cause leading to hepatic graft loss and subsequent retransplantation was biliary complications in 36 patients (45%). The patients underwent retransplantation more than 30 days after their primary transplant recovered better than those who underwent retransplantation within 8-30 days after primary transplantation (perioperative mortality 19.6% versus 70%). Sepsis (12 of 22 patients, 54.5%) and multiple organ failure (4 of 22 patients, 18.2%) were leading causes of re-OLT recipient deaths.<br />Conclusions: Proper indications and optimal operative time, surgical procedures, perioperative monitoring and appropriate postoperative treatment contribute to the improvement of the survival rate of patients after liver retransplantation.
- Subjects :
- Adolescent
Adult
Age Distribution
Aged
China
Cohort Studies
Female
Graft Rejection pathology
Graft Survival
Humans
Liver Transplantation methods
Male
Middle Aged
Prognosis
Reoperation methods
Reoperation statistics & numerical data
Retrospective Studies
Risk Assessment
Sex Distribution
Survival Rate
Transplantation, Homologous
Cause of Death
Graft Rejection surgery
Liver surgery
Liver Transplantation adverse effects
Liver Transplantation mortality
Subjects
Details
- Language :
- English
- ISSN :
- 1499-3872
- Volume :
- 5
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Hepatobiliary & pancreatic diseases international : HBPD INT
- Publication Type :
- Academic Journal
- Accession number :
- 16698571