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A case of cholesterol embolism confirmed by skin biopsy and successfully treated with statins and steroids.
- Source :
-
The American journal of the medical sciences [Am J Med Sci] 2006 May; Vol. 331 (5), pp. 280-3. - Publication Year :
- 2006
-
Abstract
- Although cholesterol embolism syndrome was recognized as a clinicopathologic entity more than 50 years ago, it is attracting growing attention recently. It is a multisystemic disorder in which cholesterol crystals released from atherosclerotic plaques obstruct small arterioles, resulting in local ischemia and end-organ damage. There are no established treatments, and with the limited treatment options available, it is important to make the diagnosis as early as possible. We present the case of a 68-year-old man with cholesterol embolism who had a few fluttering atheromas in the aorta, as demonstrated by transesophageal ultrasonography. The diagnosis was confirmed by skin biopsy, and treatment with statins and steroids proved effective, as renal failure progressively improved. This case emphasizes the importance of early diagnosis and shows the possible therapeutic effects of statins and steroids for patients with this syndrome.
- Subjects :
- Aged
Atorvastatin
Biopsy
Blue Toe Syndrome diagnosis
Blue Toe Syndrome drug therapy
Blue Toe Syndrome pathology
Diagnosis, Differential
Embolism, Cholesterol pathology
Heptanoic Acids therapeutic use
Humans
Male
Prednisolone therapeutic use
Pyrroles therapeutic use
Simvastatin therapeutic use
Skin drug effects
Skin pathology
Skin Diseases, Vascular diagnosis
Embolism, Cholesterol diagnosis
Embolism, Cholesterol drug therapy
Hydroxymethylglutaryl-CoA Reductase Inhibitors therapeutic use
Skin Diseases, Vascular pathology
Steroids therapeutic use
Subjects
Details
- Language :
- English
- ISSN :
- 0002-9629
- Volume :
- 331
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- The American journal of the medical sciences
- Publication Type :
- Academic Journal
- Accession number :
- 16702800
- Full Text :
- https://doi.org/10.1097/00000441-200605000-00010