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[Becker's nevus associated with epidermal nevus: another example of twin spotting?].
- Source :
-
Actas dermo-sifiliograficas [Actas Dermosifiliogr] 2006 Apr; Vol. 97 (3), pp. 200-2. - Publication Year :
- 2006
-
Abstract
- Linear epidermal nevi are believed to be caused by an autosomal dominant lethal mutation that can only be expressed by mosaicism. Becker's nevus can be explained by paradominant inheritance which is only manifested clinically by an acquired loss of heterozygosity. We present the case of a 16-year-old female with an epidermal nevus located on the left side of the neck, and also a Becker's nevus located on the ipsilateral shoulder. It is interesting to speculate that this supposed double mosaicism could be another example of "twin spotting" or non-allelic didymosis, although the possibility that this is a chance association cannot be ruled out, as the lesions are not closely associated.
- Subjects :
- Adolescent
Female
Hamartoma embryology
Head and Neck Neoplasms embryology
Humans
Loss of Heterozygosity
Nevus, Pigmented embryology
Shoulder
Skin Diseases embryology
Skin Neoplasms embryology
Hamartoma genetics
Head and Neck Neoplasms genetics
Mosaicism
Nevus, Pigmented genetics
Skin Diseases genetics
Skin Neoplasms genetics
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0001-7310
- Volume :
- 97
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Actas dermo-sifiliograficas
- Publication Type :
- Academic Journal
- Accession number :
- 16796968
- Full Text :
- https://doi.org/10.1016/s0001-7310(06)73380-4