Sulfonylurea treatment outweighs insulin therapy in short-term metabolic control of patients with permanent neonatal diabetes mellitus due to activating mutations of the KCNJ11 (KIR6.2) gene.

Authors :: Tonini G
Bizzarri C
Bonfanti R
Vanelli M
Cerutti F
Faleschini E
Meschi F
Prisco F
Ciacco E
Cappa M
Torelli C
Cauvin V
Tumini S
Iafusco D
Barbetti F
Source :: Diabetologia [Diabetologia] 2006 Sep; Vol. 49 (9), pp. 2210-3. Date of Electronic Publication: 2006 Jul 01.
Publication Year :: 2006

Subjects :: Amino Acid Substitution
Blood Glucose metabolism
Child
Diabetes Mellitus blood
Diabetes Mellitus genetics
Humans
Hypoglycemic Agents therapeutic use
Infant
Infant, Newborn
Infant, Newborn, Diseases drug therapy
Infant, Newborn, Diseases genetics
Infant, Newborn, Diseases metabolism
Treatment Outcome
Diabetes Mellitus drug therapy
Insulin therapeutic use
Mutation
Potassium Channels, Inwardly Rectifying genetics
Sulfonylurea Compounds therapeutic use

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