Back to Search
Start Over
What if higher plants lack a CDC25 phosphatase?
- Source :
-
Trends in plant science [Trends Plant Sci] 2006 Oct; Vol. 11 (10), pp. 474-9. Date of Electronic Publication: 2006 Sep 01. - Publication Year :
- 2006
-
Abstract
- Progression through the cell cycle is regulated by cyclin-dependent kinases (CDKs). Plants possess a unique class of CDKs, designated B-type CDKs, but seem to lack a functional CDC25 phosphatase, which is a crucial activator of the onset of mitosis in non-plant species. Based on a striking number of functional parallels between the Arabidopsis thaliana CDKB1;1 and the Drosophila melanogaster CDC25 (string), we hypothesize that the acquisition of B-type CDKs and the disappearance of CDC25 in plants might have been associated; in these coupled events, the CDC25-controlled onset of mitosis might have been evolutionarily replaced by a B-type CDK-dominated pathway, eventually resulting in the loss of the CDC25 gene.
- Subjects :
- Cell Cycle physiology
Cyclin-Dependent Kinases classification
Cyclin-Dependent Kinases genetics
Gene Expression Regulation, Plant
Phosphorylation
Plant Cells
Plant Development
cdc25 Phosphatases genetics
Cyclin-Dependent Kinases physiology
Evolution, Molecular
Plants enzymology
cdc25 Phosphatases physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1360-1385
- Volume :
- 11
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Trends in plant science
- Publication Type :
- Academic Journal
- Accession number :
- 16949857
- Full Text :
- https://doi.org/10.1016/j.tplants.2006.08.009