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What if higher plants lack a CDC25 phosphatase?

Authors :
Boudolf V
Inzé D
De Veylder L
Source :
Trends in plant science [Trends Plant Sci] 2006 Oct; Vol. 11 (10), pp. 474-9. Date of Electronic Publication: 2006 Sep 01.
Publication Year :
2006

Abstract

Progression through the cell cycle is regulated by cyclin-dependent kinases (CDKs). Plants possess a unique class of CDKs, designated B-type CDKs, but seem to lack a functional CDC25 phosphatase, which is a crucial activator of the onset of mitosis in non-plant species. Based on a striking number of functional parallels between the Arabidopsis thaliana CDKB1;1 and the Drosophila melanogaster CDC25 (string), we hypothesize that the acquisition of B-type CDKs and the disappearance of CDC25 in plants might have been associated; in these coupled events, the CDC25-controlled onset of mitosis might have been evolutionarily replaced by a B-type CDK-dominated pathway, eventually resulting in the loss of the CDC25 gene.

Details

Language :
English
ISSN :
1360-1385
Volume :
11
Issue :
10
Database :
MEDLINE
Journal :
Trends in plant science
Publication Type :
Academic Journal
Accession number :
16949857
Full Text :
https://doi.org/10.1016/j.tplants.2006.08.009