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Comparative genomic evidence for a close relationship between the dimorphic prosthecate bacteria Hyphomonas neptunium and Caulobacter crescentus.
- Source :
-
Journal of bacteriology [J Bacteriol] 2006 Oct; Vol. 188 (19), pp. 6841-50. - Publication Year :
- 2006
-
Abstract
- The dimorphic prosthecate bacteria (DPB) are alpha-proteobacteria that reproduce in an asymmetric manner rather than by binary fission and are of interest as simple models of development. Prior to this work, the only member of this group for which genome sequence was available was the model freshwater organism Caulobacter crescentus. Here we describe the genome sequence of Hyphomonas neptunium, a marine member of the DPB that differs from C. crescentus in that H. neptunium uses its stalk as a reproductive structure. Genome analysis indicates that this organism shares more genes with C. crescentus than it does with Silicibacter pomeroyi (a closer relative according to 16S rRNA phylogeny), that it relies upon a heterotrophic strategy utilizing a wide range of substrates, that its cell cycle is likely to be regulated in a similar manner to that of C. crescentus, and that the outer membrane complements of H. neptunium and C. crescentus are remarkably similar. H. neptunium swarmer cells are highly motile via a single polar flagellum. With the exception of cheY and cheR, genes required for chemotaxis were absent in the H. neptunium genome. Consistent with this observation, H. neptunium swarmer cells did not respond to any chemotactic stimuli that were tested, which suggests that H. neptunium motility is a random dispersal mechanism for swarmer cells rather than a stimulus-controlled navigation system for locating specific environments. In addition to providing insights into bacterial development, the H. neptunium genome will provide an important resource for the study of other interesting biological processes including chromosome segregation, polar growth, and cell aging.
- Subjects :
- Alphaproteobacteria cytology
Alphaproteobacteria physiology
Bacterial Outer Membrane Proteins genetics
Caulobacter crescentus cytology
Caulobacter crescentus physiology
Cell Cycle genetics
Chemotaxis genetics
Chemotaxis physiology
DNA, Bacterial chemistry
DNA, Bacterial genetics
Flagella physiology
Microbial Viability
Molecular Sequence Data
Movement
Sequence Analysis, DNA
Sequence Homology
Signal Transduction
Alphaproteobacteria genetics
Caulobacter crescentus genetics
Genome, Bacterial
Subjects
Details
- Language :
- English
- ISSN :
- 0021-9193
- Volume :
- 188
- Issue :
- 19
- Database :
- MEDLINE
- Journal :
- Journal of bacteriology
- Publication Type :
- Academic Journal
- Accession number :
- 16980487
- Full Text :
- https://doi.org/10.1128/JB.00111-06