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Warning: bisphosphonates and osteochemonecrosis of the jaws.
- Source :
-
Journal of the Irish Dental Association [J Ir Dent Assoc] 2006 Autumn; Vol. 52 (2), pp. 79-83. - Publication Year :
- 2006
-
Abstract
- The aim of this article is to highlight the link between bisphosphonates and osteonecrotic lesions of the jaws ("osteochemonecrosis") and to alert general practitioners to the implications these drugs may have on their day-to-day practice. We review the use of this class of drug, the indications for which have widened recently, describe their effect on bone metabolism and outline the proposed mechanism for bisphosphonate-induced osteochemonecrosis. Predisposing and initiating factors and management are outlined, and suggestions made as to how the dental profession can help with this increasingly prevalent problem.
- Subjects :
- Bone Remodeling drug effects
Dental Care adverse effects
Dental Care methods
Humans
Jaw Diseases diagnosis
Neoplasms drug therapy
Osteoclasts drug effects
Osteonecrosis diagnosis
Osteoporosis drug therapy
Risk Factors
Wound Healing physiology
Bone Density Conservation Agents adverse effects
Diphosphonates adverse effects
Jaw Diseases chemically induced
Osteonecrosis chemically induced
Subjects
Details
- Language :
- English
- ISSN :
- 0021-1133
- Volume :
- 52
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of the Irish Dental Association
- Publication Type :
- Academic Journal
- Accession number :
- 16989369