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Endemic bacterial meningitis in Sudanese children: aetiology, clinical findings, treatment and short-term outcome.
- Source :
-
Annals of tropical paediatrics [Ann Trop Paediatr] 1990; Vol. 10 (2), pp. 203-10. - Publication Year :
- 1990
-
Abstract
- During the period April 1985 to November 1986 (18 months), 196 children (of age greater than 1 month) admitted to the Children's Emergency Hospital in Khartoum, Sudan, with clinical suspicion of meningitis/meningoencephalitis were followed up prospectively. Bacterial meningitis was diagnosed by culture, direct microscopy and/or antigen-detecting assays (co-agglutination and enzyme immunoassay) in 44 infants (25 Haemophilus influenzae type b, 8 Neisseria meningitidis, 7 Streptococcus pneumoniae, 3 enterobacteria and one mixed infection), aseptic meningitis in 52, cerebral malaria in 4 and febrile convulsions in 96. The majority of cases of bacterial meningitis were boys and 57% of those in whom H. influenzae was the commonest isolate were less than 1 year old. The presenting signs and symptoms are described as well as the transient and permanent short-term sequelae. The total mortality from bacterial meningitis was 19%, permanent neurological sequelae were seen in 26% of survivors. Prospective follow-up, including audiometry, of 35 children 1-2 months after discharge showed that 11% had hemiplegia and 20% had hearing impairment. The potential impact of vaccination against invasive H. influenzae infections is discussed.
- Subjects :
- Bacterial Infections cerebrospinal fluid
Bacterial Infections complications
Bacterial Vaccines
Child
Child, Preschool
Female
Haemophilus influenzae
Hearing Disorders etiology
Hemiplegia etiology
Humans
Infant
Male
Meningitis cerebrospinal fluid
Meningitis complications
Meningitis, Aseptic epidemiology
Meningitis, Haemophilus epidemiology
Meningitis, Meningococcal epidemiology
Meningitis, Pneumococcal epidemiology
Sudan epidemiology
Bacterial Infections epidemiology
Meningitis epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 0272-4936
- Volume :
- 10
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Annals of tropical paediatrics
- Publication Type :
- Academic Journal
- Accession number :
- 1699486
- Full Text :
- https://doi.org/10.1080/02724936.1990.11747431