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[Clinical analysis in diagnosis and treatment of 11 patients with hereditary renal cell carcinoma].
- Source :
-
Zhonghua wai ke za zhi [Chinese journal of surgery] [Zhonghua Wai Ke Za Zhi] 2006 Jul 15; Vol. 44 (14), pp. 963-5. - Publication Year :
- 2006
-
Abstract
- Objective: To evaluate the diagnosis and treatment of hereditary renal cell carcinoma.<br />Methods: Clinical data of 11 patients with hereditary renal cell carcinoma were analyzed retrospectively. Eight patients were male and 3 were female, age ranged from 32 to 67 (mean: age 48 years). Four cases were bilateral renal cell carcinoma, and 4 were multiple renal cell carcinoma. Two cases were diagnosed as Von Hippel-Lindau syndrome, 6 as familial clear cell renal cell cancer, and 3 as hereditary papillary renal carcinoma.<br />Results: Ten patients performed nephron-sparing surgery and/or radical nephrectomy and 1 had no operation. The patients were followed up from 12 to 114 months. Tumor recurrence was observed in 4 patients, 1 patient died of tumor metastasis, and 2 died of other causes. Four patients survived free of tumor.<br />Conclusions: Hereditary renal carcinoma appears in the youth, and it is predominantly multiple and bilateral. Nephron-sparing surgery is the standard method of treatment for the patients.
Details
- Language :
- Chinese
- ISSN :
- 0529-5815
- Volume :
- 44
- Issue :
- 14
- Database :
- MEDLINE
- Journal :
- Zhonghua wai ke za zhi [Chinese journal of surgery]
- Publication Type :
- Academic Journal
- Accession number :
- 17074206