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Pancreatic abscess caused by Corynebacterium coyleae mimicking malignant neoplasm.
- Source :
-
Pancreas [Pancreas] 2006 Nov; Vol. 33 (4), pp. 425-9. - Publication Year :
- 2006
-
Abstract
- A 50-year-old female was referred to our hospital because of postprandial epigastric pain and pancreatic head mass. On admission, an elastic hard mass with tenderness was palpable in the epigastric region. Laboratory findings showed no abnormalities, except for a slightly elevated C-reactive protein value and iron deficiency anemia. Serum levels of pancreatic enzymes and tumor markers were also within the reference range. Computed tomography (CT) demonstrated a 5-cm heterogenous mass at the head of the pancreas. Angiography showed that gastroduodenal artery was transformed and narrowed by the mass. Smooth stenosis of portal vein was also observed. Fusion CT-positron emission tomography with 2-deoxy-2-[F]fluoro-D-glucose demonstrated a focus of increased uptake in the pancreatic head mass. We suspected the mass of malignancy but, surprisingly, tumor size was gradually decreased without any therapies. Biopsy specimens from the mass of the pancreas showed marked inflammatory cell infiltration and marked interstitial fibrosis without malignant cells. Thereafter, we could isolate Corynebacterium coyleae from the biopsy specimen. We diagnosed the mass as a pancreatic abscess caused by C. coyleae and started with the intravenous antibiotics therapy. Subsequent follow-up CT and ultrasonography showed dramatic improvement in pancreatic mass. We present here a case of pancreatic abscess which was difficult to differentiate from malignant lesion by various imaging studies. Moreover, we could culture and identify C. coyleae which had never been reported to be the source of pancreatic abscess.
- Subjects :
- Abscess etiology
Abscess microbiology
Angiography
Corynebacterium isolation & purification
Corynebacterium Infections complications
Diagnosis, Differential
Female
Humans
Middle Aged
Pancreatic Diseases etiology
Pancreatic Diseases microbiology
Positron-Emission Tomography
Tomography, X-Ray Computed
Abscess diagnosis
Corynebacterium Infections diagnosis
Pancreatic Diseases diagnosis
Pancreatic Neoplasms diagnosis
Subjects
Details
- Language :
- English
- ISSN :
- 1536-4828
- Volume :
- 33
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Pancreas
- Publication Type :
- Academic Journal
- Accession number :
- 17079950
- Full Text :
- https://doi.org/10.1097/01.mpa.0000236730.08747.69