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The radiologic manifestations of H5N1 avian influenza.

The radiologic manifestations of H5N1 avian influenza.

Authors :
Qureshi NR
Hien TT
Farrar J
Gleeson FV
Source :
Journal of thoracic imaging [J Thorac Imaging] 2006 Nov; Vol. 21 (4), pp. 259-64.
Publication Year :
2006

Abstract

Avian influenza is caused by the H5N1 subtype of the influenza A virus. Human transmission is either directly through close contact with infected birds usually poultry or their secretions. To date 178 people throughout South East Asia have been infected with 85 deaths. Patients usually present with a rapidly progressive pneumonia that can result in respiratory failure and acute respiratory distress syndrome. The chest radiograph therefore remains the most convenient and accessible imaging modality. Studies have shown that most radiographs are abnormal at the time of presentation with multifocal consolidation the commonest radiographic finding. During the course of disease, pleural effusions and cavitation can also develop. Consolidation that involves > or = 4 zones on presentation or at day 7 after the onset of symptoms and subsequent development of acute respiratory distress syndrome are generally associated with an adverse outcome. Chest CT examinations performed during the convalescent period have demonstrated persistent ground glass attenuation and segmental consolidation. Additional features included pseudocavitation, pneumatocoele formation, lymphadenopathy, and centrilobular nodules. Overall the appearances are suggestive of mild fibrosis.

Details

Language :
English
ISSN :
0883-5993
Volume :
21
Issue :
4
Database :
MEDLINE
Journal :
Journal of thoracic imaging
Publication Type :
Academic Journal
Accession number :
17110849
Full Text :
https://doi.org/10.1097/01.rti.0000213573.94032.53