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Direct comparison of peripheral T-cell lymphomas with their B-cell counterpart.
- Source :
-
Acta haematologica [Acta Haematol] 1991; Vol. 85 (4), pp. 179-83. - Publication Year :
- 1991
-
Abstract
- The aim of this study was to determine the effect of immunophenotype on the clinical characteristics and prognosis of 144 adult Chinese patients with non-Hodgkin's lymphomas. Those entities with well-recognised immunophenotype and clinical characteristics were excluded. Significantly more patients with T-cell lymphomas had B symptoms (52 vs. 30%, p = 0.05) and fewer had bulky disease (7 vs. 25%, p = 0.04). Extranodal involvements of liver, spleen, marrow, nasal region and skin were significantly more common in T-cell lymphomas. On the other hand, gastro-intestinal involvement was more commonly seen in B-cell tumours. Induction chemotherapy of comparable intensity was used in treating these patients. The immunophenotype did not appear to affect significantly their prognosis.
- Subjects :
- Antineoplastic Combined Chemotherapy Protocols therapeutic use
Bleomycin therapeutic use
China
Cyclophosphamide therapeutic use
Dexamethasone therapeutic use
Doxorubicin therapeutic use
Female
Humans
Immunophenotyping
Leucovorin therapeutic use
Lomustine therapeutic use
Male
Methotrexate therapeutic use
Middle Aged
Prednisone therapeutic use
Procarbazine therapeutic use
Survival Rate
Vinblastine therapeutic use
Vincristine therapeutic use
Lymphoma, B-Cell drug therapy
Lymphoma, B-Cell mortality
Lymphoma, B-Cell pathology
Lymphoma, T-Cell drug therapy
Lymphoma, T-Cell mortality
Lymphoma, T-Cell pathology
Subjects
Details
- Language :
- English
- ISSN :
- 0001-5792
- Volume :
- 85
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Acta haematologica
- Publication Type :
- Academic Journal
- Accession number :
- 1713011
- Full Text :
- https://doi.org/10.1159/000204887