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Changes in treatment of advanced laryngeal cancer 1985-2001.
- Source :
-
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery [Otolaryngol Head Neck Surg] 2006 Dec; Vol. 135 (6), pp. 831-7. - Publication Year :
- 2006
-
Abstract
- Objective: In 1991, a randomized study was published and demonstrated that use of nonsurgical therapy (chemoradiation) provided similar survival to total laryngectomy (the gold standard) for patients with advanced-stage laryngeal cancer. The purpose of this study was to assess how treatment of advanced laryngeal cancer was influenced by such developments in non-surgical therapy.<br />Study Design: Patterns of care study using National Cancer Database (1985-2001).<br />Results: The percentage of advanced-stage patients treated with chemoradiation increased from 8.3% to 20.8% while the proportion treated with radiation alone decreased from 38.9% to 23.0%. Use of chemoradiation increased at a significantly faster rate after the 1991 publication at both community cancer centers and teaching research facilities. The use of total laryngectomy decreased slightly during this period.<br />Conclusions: The use of chemoradiation increased after the 1991 publication. It was impossible to determine from the NCDB whether additional patients who could benefit from chemo-RT were not offered or did not complete this treatment option. We recommend that treatment recommendations discussed at tumor boards be recorded in cancer registries.
- Subjects :
- Aged
Cancer Care Facilities statistics & numerical data
Combined Modality Therapy
Female
Hospitals, Community statistics & numerical data
Hospitals, Teaching statistics & numerical data
Humans
Laryngectomy statistics & numerical data
Laryngectomy trends
Male
Middle Aged
United States
Antineoplastic Agents therapeutic use
Laryngeal Neoplasms drug therapy
Laryngeal Neoplasms radiotherapy
Medical Oncology trends
Subjects
Details
- Language :
- English
- ISSN :
- 0194-5998
- Volume :
- 135
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
- Publication Type :
- Academic Journal
- Accession number :
- 17141069
- Full Text :
- https://doi.org/10.1016/j.otohns.2006.07.012