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Detection of Tsh protein mucinolytic activity by SDS-PAGE.

Authors :
Kobayashi RK
Gaziri LC
Venancio EJ
Vidotto MC
Source :
Journal of microbiological methods [J Microbiol Methods] 2007 Mar; Vol. 68 (3), pp. 654-5. Date of Electronic Publication: 2006 Dec 08.
Publication Year :
2007

Abstract

The temperature-sensitive hemagglutinin (Tsh, 140 kDa) produced by Escherichia coli is cleaved into a fragment (106 kDa) containing mucinase activity, and an agglutinin fragment (33 kDa). By incorporating mucins into SDS-PAGE gels stained by Schiff's periodic acid, we could simultaneously detect about 0.5 microg of mucinase activity and the fragment molecular mass.

Details

Language :
English
ISSN :
0167-7012
Volume :
68
Issue :
3
Database :
MEDLINE
Journal :
Journal of microbiological methods
Publication Type :
Academic Journal
Accession number :
17157399
Full Text :
https://doi.org/10.1016/j.mimet.2006.10.002