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Enantioselective synthesis of C3 fluoro-MEP.

Authors :
Ghilagaber S
Hunter WN
Marquez R
Source :
Organic & biomolecular chemistry [Org Biomol Chem] 2007 Jan 07; Vol. 5 (1), pp. 97-102. Date of Electronic Publication: 2006 Nov 10.
Publication Year :
2007

Abstract

The first enantioselective synthesis of C(3) fluoro-MEP is herein reported. The synthetic pathway developed takes advantage of a selective hydrofluorination of a 2,3-epoxy-1-alcohol to introduce the required tertiary fluoride unit.

Details

Language :
English
ISSN :
1477-0520
Volume :
5
Issue :
1
Database :
MEDLINE
Journal :
Organic & biomolecular chemistry
Publication Type :
Academic Journal
Accession number :
17164912
Full Text :
https://doi.org/10.1039/b613656g