Monitoring serum free light chains in patients with multiple myeloma who achieved negative immunofixation after allogeneic stem cell transplantation.

Authors :: Mösbauer U
Ayuk F
Schieder H
Lioznov M
Zander AR
Kröger N
Source :: Haematologica [Haematologica] 2007 Feb; Vol. 92 (2), pp. 275-6.
Publication Year :: 2007
Abstract: Monitoring of serum free immunoglobulin light chains (FLC) in 26 myeloma patients who achieved immunofixation negativity after allografting showed a decrease of FLC at a median of 128 days before immunofixation negativity. In patients who subsequently relapsed, a 25% increase of FLC was observed at a median of 98 days before immunofixation positivity.

Subjects :: Adult
Binding Sites
Biomarkers, Tumor blood
Female
Follow-Up Studies
Humans
Male
Middle Aged
Remission Induction
Time Factors
Treatment Outcome
Immunoglobulin Light Chains blood
Multiple Myeloma blood
Multiple Myeloma therapy
Stem Cell Transplantation methods

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