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Clinical impact of multidetector row computed tomography on patients with pancreatic cancer.

Authors :
Satoi S
Yamamoto H
Takai S
Tanigawa N
Komemushi A
Yanagimoto H
Toyokawa H
Matsui Y
Mergental H
Kamiyama Y
Source :
Pancreas [Pancreas] 2007 Mar; Vol. 34 (2), pp. 175-9.
Publication Year :
2007

Abstract

Objectives: This study was designed to compare multidetector row computed tomography (MDCT) and CT-assisted hepatic arteriography (CTHA)/CT during arterial portography (CTAP)/angiography/contrast-enhanced CT (CECT) findings prospectively for accuracy in the detection of liver metastasis and vascular involvement of the tumor.<br />Methods: The study included 43 patients with pancreatic cancer who were evaluated from September 2002 to December 2003. These patients underwent preoperative evaluation by angiography/CTHA/CTAP/CECT (7-mm thickness) and by MDCT (1.25-mm thickness).<br />Results: The sensitivity, specificity, positive predictive value, and negative predictive value of liver metastasis diagnosis were all superior using MDCT relative to CTHA/CTAP. The diagnostic accuracy of liver metastasis for patients with tumors less than 10 mm in diameter was particularly superior with MDCT relative to CTHA/CTAP. The surgical and pathological findings of vascular involvement were more accurately diagnosed by MDCT than by CTHA/CTAP/angiography/CECT. Although MDCT findings were generally similar to surgical findings of vascular involvement, MDCT overestimated the incidence of pathological vascular involvement.<br />Conclusions: Multidetector row CT imaging can potentially offer more accurate staging of pancreatic cancer and may be useful to surgeons both in preoperative planning and for intraoperative guidance.

Details

Language :
English
ISSN :
1536-4828
Volume :
34
Issue :
2
Database :
MEDLINE
Journal :
Pancreas
Publication Type :
Academic Journal
Accession number :
17312454
Full Text :
https://doi.org/10.1097/MPA.0b013e31802e7107