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Continuous veno-venous hemofiltration in the treatment of acute severe hyponatremia: a report of 11 cases.
- Source :
-
The International journal of artificial organs [Int J Artif Organs] 2007 Feb; Vol. 30 (2), pp. 176-80. - Publication Year :
- 2007
-
Abstract
- Objectives: To evaluate the treatment effect of continuous veno-venous hemofiltration (CVVH) in patients with acute severe hyponatremia.<br />Methods: Eleven patients with severe acute hyponatremia, including 6 males and 5 females, aged 25-61 years (mean age 48.36), were treated with CVVH. Hyponatremia occurred 38-48 hours prior to the initiation of CVVH.<br />Results: All patients tolerated CVVH well, with an average treatment duration of 57.19 (45.6-86) hours. During CVVH, the serum sodium concentration increased significantly from 100.9+/-3.99 mmol/L at initiation of CVVH to 140.3+/-1.6 mmol/L after 48 hours of treatment (P<0.01). The serum osmolarity increased concurrently, from 216.7+/-7.4 mOsm/kgH2O to 295.0+/-4.2 mOsm/kgH2O (P<0.01). The Glasgow scores and APACHE II scores in these patients improved significantly during treatment.<br />Conclusions: CVVH is a safe and effective option for the treatment of patients with severe acute hyponatremia due to its slow and continuous nature.
Details
- Language :
- English
- ISSN :
- 0391-3988
- Volume :
- 30
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- The International journal of artificial organs
- Publication Type :
- Academic Journal
- Accession number :
- 17377913
- Full Text :
- https://doi.org/10.1177/039139880703000213