Investigation on 1,4-dichlorophthalazine-derivatized cinchona alkaloids-catalyzed asymmetric "interrupted" Feist-Bénary reaction.

Different 1,4-dichlorophthalazine-cinchona alkaloid derivatives have been used to catalyze the asymmetric "interrupted" Feist-Bénary reaction of ethyl bromopyruvate/substituted bromoketoesters and beta-dicarbonyl compounds. The corresponding hydroxydihydrofurans have been obtained in excellent yields and with up to 91%ee.