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Low-dose oral tri-iodothyronine does not directly increase food intake in man.

Authors :
Martin NM
Small CJ
Lee JL
Ellis S
Dhillo WS
Smith KL
Kong WM
Frost GS
Bloom SR
Source :
Diabetes, obesity & metabolism [Diabetes Obes Metab] 2007 May; Vol. 9 (3), pp. 435-7.
Publication Year :
2007

Abstract

Previously, we have shown that low-dose tri-iodothyronine (T3) increases food intake in rodents. This randomised, double-blind, placebo-controlled study aimed to investigate the effects of low-dose T3 on food intake in normal body weight individuals. However, despite an elevation in fT3 comparable to our earlier studies, administration of low-dose T3 in the fasted state did not stimulate food intake in man.

Details

Language :
English
ISSN :
1462-8902
Volume :
9
Issue :
3
Database :
MEDLINE
Journal :
Diabetes, obesity & metabolism
Publication Type :
Academic Journal
Accession number :
17391172
Full Text :
https://doi.org/10.1111/j.1463-1326.2006.00613.x