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Two new antifungal alkaloids produced by Streptoverticillium morookaense.
- Source :
-
The Journal of antibiotics [J Antibiot (Tokyo)] 2007 Mar; Vol. 60 (3), pp. 179-83. - Publication Year :
- 2007
-
Abstract
- A new carbazole alkaloid, streptoverticillin, and a new 2-azetidinone, streptoverticillinone, along with three known cyclodipeptides were isolated from the mycelial solid culture of Streptoverticillium morookaense. Their structures were elucidated by analysis of 1D and 2D NMR, mass spectra and optical rotation data. Two new compounds exhibited antifungal activity against Peronophythora litchii.
- Subjects :
- Alkaloids chemistry
Alkaloids isolation & purification
Antifungal Agents chemistry
Antifungal Agents isolation & purification
Carbazoles chemistry
Carbazoles isolation & purification
Carbazoles pharmacology
Litchi microbiology
Magnetic Resonance Spectroscopy
Mass Spectrometry methods
Microbial Sensitivity Tests
Optical Rotation
Plant Diseases microbiology
Pyrrolidines chemistry
Pyrrolidines isolation & purification
Pyrrolidines pharmacology
Streptomyces growth & development
Alkaloids biosynthesis
Alkaloids pharmacology
Antifungal Agents metabolism
Antifungal Agents pharmacology
Fungi drug effects
Streptomyces metabolism
Subjects
Details
- Language :
- English
- ISSN :
- 0021-8820
- Volume :
- 60
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- The Journal of antibiotics
- Publication Type :
- Academic Journal
- Accession number :
- 17446689
- Full Text :
- https://doi.org/10.1038/ja.2007.19