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Design and synthesis of 2,3,5-substituted imidazolidin-4-one inhibitors of BACE-1.
- Source :
-
ChemMedChem [ChemMedChem] 2007 Jul; Vol. 2 (7), pp. 995-9. - Publication Year :
- 2007
- Subjects :
- Amyloid Precursor Protein Secretases chemistry
Aspartic Acid Endopeptidases chemistry
Binding Sites
Crystallography, X-Ray
Hydrogen Bonding
Imidazolidines chemistry
Mass Spectrometry
Models, Molecular
Protease Inhibitors chemistry
Amyloid Precursor Protein Secretases antagonists & inhibitors
Aspartic Acid Endopeptidases antagonists & inhibitors
Imidazolidines chemical synthesis
Imidazolidines pharmacology
Protease Inhibitors chemical synthesis
Protease Inhibitors pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1860-7187
- Volume :
- 2
- Issue :
- 7
- Database :
- MEDLINE
- Journal :
- ChemMedChem
- Publication Type :
- Academic Journal
- Accession number :
- 17458843
- Full Text :
- https://doi.org/10.1002/cmdc.200700038