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Management of antiretroviral treatment-related complications.
- Source :
-
Infectious disease clinics of North America [Infect Dis Clin North Am] 2007 Mar; Vol. 21 (1), pp. 103-32, ix. - Publication Year :
- 2007
-
Abstract
- Antiretroviral therapy for HIV restores immune function, controls viral replication, decreases opportunistic infections, and extends lifespan to near-normal for infected individuals. However, successful HIV therapy has been accompanied by the emergence of treatment-related complications, with an impact not yet fully understood. This article reviews six common complications of antiretroviral therapy, including hyperlactatemia/lactic acidosis, hypersensitivity reactions, abnormal glucose metabolism, dyslipidemia, body composition changes, and cardiovascular disease. A comprehensive approach to management of antiretroviral-related complications includes awareness of (1) risk factors for adverse reactions, (2) clinical syndromes suggestive of an evolving complication, and (3) evidence-based monitoring and treatment strategies. Fluency in options for preventing and managing complications can provide maximal opportunity to balance treatment effects with quality of life.
Details
- Language :
- English
- ISSN :
- 0891-5520
- Volume :
- 21
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Infectious disease clinics of North America
- Publication Type :
- Academic Journal
- Accession number :
- 17502232
- Full Text :
- https://doi.org/10.1016/j.idc.2007.01.007