VIPER: an advanced software package to support high-throughput LC-MS peptide identification.

Authors :: Monroe ME
Tolić N
Jaitly N
Shaw JL
Adkins JN
Smith RD
Source :: Bioinformatics (Oxford, England) [Bioinformatics] 2007 Aug 01; Vol. 23 (15), pp. 2021-3. Date of Electronic Publication: 2007 Jun 01.
Publication Year :: 2007
Abstract: Summary: The accurate mass and time (AMT) tag approach is used for analysis of large scale experiments by combining information generated over multiple datasets and instrument types. The VIPER software package is one of the key components of the data processing pipeline and implements automated algorithms to discover LC-MS features, align and match these LC-MS features to a database of peptides previously identified in LC-MS/MS analyses, and identify and quantify pairs of isotopically labeled peptides.<br />Availability: VIPER may be downloaded free of charge at http://ncrr.pnl.gov/software/

Subjects :: Amino Acid Sequence
Molecular Sequence Data
Algorithms
Chromatography, Liquid methods
Mass Spectrometry methods
Peptide Mapping methods
Peptides chemistry
Sequence Analysis, Protein methods
Software
User-Computer Interface

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