LongSAGE profiling of nine human embryonic stem cell lines.

Authors :: Hirst M
Delaney A
Rogers SA
Schnerch A
Persaud DR
O'Connor MD
Zeng T
Moksa M
Fichter K
Mah D
Go A
Morin RD
Baross A
Zhao Y
Khattra J
Prabhu AL
Pandoh P
McDonald H
Asano J
Dhalla N
Ma K
Lee S
Ally A
Chahal N
Menzies S
Siddiqui A
Holt R
Jones S
Gerhard DS
Thomson JA
Eaves CJ
Marra MA
Source :: Genome biology [Genome Biol] 2007; Vol. 8 (6), pp. R113.
Publication Year :: 2007
Abstract: To facilitate discovery of novel human embryonic stem cell (ESC) transcripts, we generated 2.5 million LongSAGE tags from 9 human ESC lines. Analysis of this data revealed that ESCs express proportionately more RNA binding proteins compared with terminally differentiated cells, and identified novel ESC transcripts, at least one of which may represent a marker of the pluripotent state.