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Angioscopic findings after drug-eluting stent implantation.
- Source :
-
Herz [Herz] 2007 Jun; Vol. 32 (4), pp. 281-6. - Publication Year :
- 2007
-
Abstract
- In-stent restenosis is the Achilles' heel of standard or bare-metal stent (BMS) implantation, occurring in 10-40% of the patients. Drug-eluting stent (DES) are supposed to inhibit inflammation and neointimal growth and, subsequently, in-stent restenosis. The neointimal proliferation inside the stent is recognized as lumen late loss on angiograms or as an obstruction area (or volume) on intravascular ultrasound (IVUS) in chronic phase. Coronary angioscopy provides direct visualization of the lumen and is capable of macroscopic pathologic diagnosis of atherosclerotic plaques and intracoronary thrombi. This modality is also able to supply detailed information on stent coverage with neointimal hyperplasia. The neointimal growth inside the stent is evaluated as white neointimal coverage over the stent struts. Angioscopic view inside the DES is quite different from that inside the BMS. In this article, the difference in angioscopic findings between the DES and the BMS is shown.
- Subjects :
- Drug Implants administration & dosage
Graft Occlusion, Vascular etiology
Graft Occlusion, Vascular prevention & control
Humans
Immunosuppressive Agents administration & dosage
Prosthesis Design
Public Policy
Thrombosis chemically induced
Thrombosis prevention & control
Treatment Outcome
Angioscopy methods
Blood Vessel Prosthesis adverse effects
Drug Implants adverse effects
Graft Occlusion, Vascular pathology
Immunosuppressive Agents adverse effects
Stents adverse effects
Subjects
Details
- Language :
- English
- ISSN :
- 0340-9937
- Volume :
- 32
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Herz
- Publication Type :
- Academic Journal
- Accession number :
- 17607534
- Full Text :
- https://doi.org/10.1007/s00059-007-2996-x