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Early results of coronary artery bypass graft surgery in women.
- Source :
-
Kardiologia polska [Kardiol Pol] 2007 Jun; Vol. 65 (6), pp. 627-33; discussion 634. - Publication Year :
- 2007
-
Abstract
- Background: Coronary artery disease is one of the leading causes of death among women in developed countries all over the world. Coronary artery bypass grafting (CABG) is a well established therapeutic modality to treat diffuse coronary artery atherosclerosis.<br />Aim: In this study we focused on the retrospective assessment of the early results of CABG in women as compared to the results of such treatment in men.<br />Methods: This analysis involved 2881 patients (677 women and 2204 men) who underwent CABG between 2003 and 2005. An operative technique (conventional on-pump or off-pump) was applied in a similar proportion of patients in both groups (on-pump: 59.4% of women and 59.6% of men; NS). Women were older than men and had higher body mass index. Concomitant disorders such as diabetes mellitus, hypertension and hypercholesterolaemia were noted more frequently in female patients.<br />Results: In the perioperative period, left ventricular failure requiring intra-aortic balloon pump insertion and administration of high doses of catecholamines was observed significantly more often in women than in men (22.1 vs. 16.1%, respectively; p <0.001). Perioperative myocardial infarction was diagnosed more frequently in women (5.5 vs. 2.9%; p <0.001). In female patients, the rate of repeat operation was higher (8.9 versus 5.1%; p <0.001) and more subjects required blood transfusions (45.5 vs. 27.5%; p <0.001). Female gender featured a higher rate of postoperative acute renal failure requiring renal replacement therapy (8.5 vs. 0.95%; p <0.001). Mechanical ventilation was longer, and women stayed longer in the postoperative intensive care unit as well as in hospital. Early postoperative mortality among women was 3.6%, i.e. significantly higher than in male patients (1.6%) (p <0.01).<br />Conclusions: The analysis performed herein suggests that mortality and morbidity after CABG is higher in women than in men.
- Subjects :
- Acute Kidney Injury mortality
Blood Loss, Surgical mortality
Comorbidity
Coronary Artery Bypass
Diabetes Mellitus epidemiology
Female
Humans
Hypercholesterolemia epidemiology
Hypertension epidemiology
Intra-Aortic Balloon Pumping statistics & numerical data
Male
Middle Aged
Myocardial Infarction mortality
Retrospective Studies
Sex Factors
Treatment Outcome
Ventricular Dysfunction, Left mortality
Coronary Artery Disease mortality
Coronary Artery Disease surgery
Postoperative Complications mortality
Subjects
Details
- Language :
- English
- ISSN :
- 0022-9032
- Volume :
- 65
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Kardiologia polska
- Publication Type :
- Academic Journal
- Accession number :
- 17629824