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[Learning to solve a spatial task in a water maze in aggressive and submissive mice].

Authors :
Dubrovina NI
Tomilenko RA
Source :
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova [Zh Vyssh Nerv Deiat Im I P Pavlova] 2007 May-Jun; Vol. 57 (3), pp. 366-72.
Publication Year :
2007

Abstract

Learning and retention of the spatial memory were studied in mice with alternative under conditions of various experimental protocols. Visible and hidden platform acquisition in a simple model of the water maze was similarly fast both in aggressive and submissive mice, but extinction differed. Retention of the platform location preference persisted in aggressive mice in four testing trials. In submissive mice, extiction of the spatial memory was accompanied with a prolongation of search with parallel production of episodes of "passive drift". Differences in spatial learning between aggressive and submissive mice were revealed in a water maze complicated with partitions. In this case, aggressors were able to learn the position of a hidden platform (in contrast to submissive mice with the dominant response of "passive drift"). During testing the response, aggressive mice longer retained the spatial preference without extinction.

Details

Language :
Russian
ISSN :
0044-4677
Volume :
57
Issue :
3
Database :
MEDLINE
Journal :
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova
Publication Type :
Academic Journal
Accession number :
17642379