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The relationship between red cell aging and enzyme activities in experimental animals.
- Source :
-
Comparative biochemistry and physiology. B, Comparative biochemistry [Comp Biochem Physiol B] 1991; Vol. 99 (2), pp. 313-6. - Publication Year :
- 1991
-
Abstract
- 1. The relationship between red cell aging and enzyme activities was studied in rabbit, guinea-pig, hamster, rats (F344/N and SD), and mice (BALB/c and DBA/2). 2. The activities of six enzymes: glucose-6-phosphate dehydrogenase (G-6-PD), 6-phosphogluconate dehydrogenase (6-PGD), hexokinase (Hx), glutamate oxaloacetate transminase (GOT), lactate dehydrogenase (LDH) and acetylcholinesterase (AChE), were measured in the red cells of different ages which were obtained either by centrifugation or experimental anaemia. 3. Hx, AChE and GOT activities were much higher in younger red cells than in older cells, hence the activities of these enzymes may be used as an indicator of age of the cells.
- Subjects :
- Acetylcholinesterase blood
Animals
Aspartate Aminotransferases blood
Cricetinae
Erythrocytes physiology
Glucosephosphate Dehydrogenase blood
Guinea Pigs
Hexokinase blood
L-Lactate Dehydrogenase blood
Mesocricetus
Mice
Mice, Inbred Strains
Phosphogluconate Dehydrogenase blood
Rabbits
Rats
Rats, Inbred Strains
Species Specificity
Erythrocyte Aging
Erythrocytes enzymology
Subjects
Details
- Language :
- English
- ISSN :
- 0305-0491
- Volume :
- 99
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Comparative biochemistry and physiology. B, Comparative biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 1764909
- Full Text :
- https://doi.org/10.1016/0305-0491(91)90047-h