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Deoxyribonucleic acid-damaged sperm in cryopreserved-thawed specimens from cancer patients and healthy men.
- Source :
-
Fertility and sterility [Fertil Steril] 2008 Jul; Vol. 90 (1), pp. 205-8. Date of Electronic Publication: 2007 Jul 20. - Publication Year :
- 2008
-
Abstract
- A similarity was found between the percentage of thawed, DNA-damaged spermatozoa in cancer patients and that in candidates to become sperm bank donors who had low sperm cryofreezability. Both groups were significantly different from the sperm bank donor group. It is suggested that the higher rate of DNA fragmentation in sperm from cancer patients compared with sperm bank donors is apparently a result of selecting donors by the level of sperm cryofreezability (i.e., high), rather than a direct effect of an existing malignancy.
- Subjects :
- Adolescent
Adult
Case-Control Studies
Cell Survival
Centrifugation, Density Gradient
Hodgkin Disease complications
Hodgkin Disease pathology
Humans
Infertility, Male pathology
Lymphoma, Non-Hodgkin complications
Lymphoma, Non-Hodgkin pathology
Male
Reproductive Techniques, Assisted
Sperm Banks
Sperm Motility
Testicular Neoplasms complications
Testicular Neoplasms pathology
Cryopreservation
DNA Damage
Hodgkin Disease genetics
Infertility, Male genetics
Lymphoma, Non-Hodgkin genetics
Semen Preservation
Spermatozoa pathology
Testicular Neoplasms genetics
Subjects
Details
- Language :
- English
- ISSN :
- 1556-5653
- Volume :
- 90
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Fertility and sterility
- Publication Type :
- Academic Journal
- Accession number :
- 17658528
- Full Text :
- https://doi.org/10.1016/j.fertnstert.2007.05.060