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A general approach to the synthesis of 1-deoxy-L-iminosugars.

Authors :
Guaragna A
D'Errico S
D'Alonzo D
Pedatella S
Palumbo G
Source :
Organic letters [Org Lett] 2007 Aug 16; Vol. 9 (17), pp. 3473-6. Date of Electronic Publication: 2007 Jul 20.
Publication Year :
2007

Abstract

A stereoselective procedure for the preparation of non-naturally occurring deoxy iminosugars belonging to L-series has been developed. The synthesis involves the construction of the key intermediate bicycle pyperidine 8, available in few steps by the coupling of the heterocyclic synthon 3 and the readily available Garner aldehyde 4.

Details

Language :
English
ISSN :
1523-7060
Volume :
9
Issue :
17
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
17658756
Full Text :
https://doi.org/10.1021/ol7014847